LOCUS       NC_000017              18111 bp    DNA     linear   CON 06-AUG-2025
DEFINITION  Homo sapiens chromosome 17, GRCh38.p14 Primary Assembly.
ACCESSION   NC_000017 REGION: 81684011..81702121
VERSION     NC_000017.11
DBLINK      BioProject: PRJNA168
            Assembly: GCF_000001405.40
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 18111)
  AUTHORS   Gregory,S.G., Barlow,K.F., McLay,K.E., Kaul,R., Swarbreck,D.,
            Dunham,A., Scott,C.E., Howe,K.L., Woodfine,K., Spencer,C.C.,
            Jones,M.C., Gillson,C., Searle,S., Zhou,Y., Kokocinski,F.,
            McDonald,L., Evans,R., Phillips,K., Atkinson,A., Cooper,R.,
            Jones,C., Hall,R.E., Andrews,T.D., Lloyd,C., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Anderson,F., Andrew,R.W., Ashwell,R.I.,
            Aubin,K., Babbage,A.K., Bagguley,C.L., Bailey,J., Beasley,H.,
            Bethel,G., Bird,C.P., Bray-Allen,S., Brown,J.Y., Brown,A.J.,
            Buckley,D., Burton,J., Bye,J., Carder,C., Chapman,J.C., Clark,S.Y.,
            Clarke,G., Clee,C., Cobley,V., Collier,R.E., Corby,N.,
            Coville,G.J., Davies,J., Deadman,R., Dunn,M., Earthrowl,M.,
            Ellington,A.G., Errington,H., Frankish,A., Frankland,J., French,L.,
            Garner,P., Garnett,J., Gay,L., Ghori,M.R., Gibson,R., Gilby,L.M.,
            Gillett,W., Glithero,R.J., Grafham,D.V., Griffiths,C.,
            Griffiths-Jones,S., Grocock,R., Hammond,S., Harrison,E.S., Hart,E.,
            Haugen,E., Heath,P.D., Holmes,S., Holt,K., Howden,P.J., Hunt,A.R.,
            Hunt,S.E., Hunter,G., Isherwood,J., James,R., Johnson,C.,
            Johnson,D., Joy,A., Kay,M., Kershaw,J.K., Kibukawa,M.,
            Kimberley,A.M., King,A., Knights,A.J., Lad,H., Laird,G., Lawlor,S.,
            Leongamornlert,D.A., Lloyd,D.M., Loveland,J., Lovell,J., Lush,M.J.,
            Lyne,R., Martin,S., Mashreghi-Mohammadi,M., Matthews,L.,
            Matthews,N.S., McLaren,S., Milne,S., Mistry,S., Moore,M.J.,
            Nickerson,T., O'Dell,C.N., Oliver,K., Palmeiri,A., Palmer,S.A.,
            Parker,A., Patel,D., Pearce,A.V., Peck,A.I., Pelan,S., Phelps,K.,
            Phillimore,B.J., Plumb,R., Rajan,J., Raymond,C., Rouse,G.,
            Saenphimmachak,C., Sehra,H.K., Sheridan,E., Shownkeen,R., Sims,S.,
            Skuce,C.D., Smith,M., Steward,C., Subramanian,S., Sycamore,N.,
            Tracey,A., Tromans,A., Van Helmond,Z., Wall,M., Wallis,J.M.,
            White,S., Whitehead,S.L., Wilkinson,J.E., Willey,D.L., Williams,H.,
            Wilming,L., Wray,P.W., Wu,Z., Coulson,A., Vaudin,M., Sulston,J.E.,
            Durbin,R., Hubbard,T., Wooster,R., Dunham,I., Carter,N.P.,
            McVean,G., Ross,M.T., Harrow,J., Olson,M.V., Beck,S., Rogers,J.,
            Bentley,D.R., Banerjee,R., Bryant,S.P., Burford,D.C., Burrill,W.D.,
            Clegg,S.M., Dhami,P., Dovey,O., Faulkner,L.M., Gribble,S.M.,
            Langford,C.F., Pandian,R.D., Porter,K.M. and Prigmore,E.
  TITLE     The DNA sequence and biological annotation of human chromosome 1
  JOURNAL   Nature 441 (7091), 315-321 (2006)
   PUBMED   16710414
  REMARK    Erratum:[Nature. 2006 Oct 26;443(7114):1013. Banerjee, R [added];
            Bryant, SP [added]; Burford, DC [added]; Burrill, WDH [added];
            Clegg, SM [added]; Dhami, P [added]; Dovey, O [added]; Faulkner, LM
            [added]; Gribble, SM [added]; Langford, CF [added]; Pandian, RD
            [added]; Porter, KM [added]; Prigmore, E [added]]
REFERENCE   2  (bases 1 to 18111)
  AUTHORS   Zody,M.C., Garber,M., Adams,D.J., Sharpe,T., Harrow,J.,
            Lupski,J.R., Nicholson,C., Searle,S.M., Wilming,L., Young,S.K.,
            Abouelleil,A., Allen,N.R., Bi,W., Bloom,T., Borowsky,M.L.,
            Bugalter,B.E., Butler,J., Chang,J.L., Chen,C.K., Cook,A., Corum,B.,
            Cuomo,C.A., de Jong,P.J., DeCaprio,D., Dewar,K., FitzGerald,M.,
            Gilbert,J., Gibson,R., Gnerre,S., Goldstein,S., Grafham,D.V.,
            Grocock,R., Hafez,N., Hagopian,D.S., Hart,E., Norman,C.H.,
            Humphray,S., Jaffe,D.B., Jones,M., Kamal,M., Khodiyar,V.K.,
            LaButti,K., Laird,G., Lehoczky,J., Liu,X., Lokyitsang,T.,
            Loveland,J., Lui,A., Macdonald,P., Major,J.E., Matthews,L.,
            Mauceli,E., McCarroll,S.A., Mihalev,A.H., Mudge,J., Nguyen,C.,
            Nicol,R., O'Leary,S.B., Osoegawa,K., Schwartz,D.C., Shaw-Smith,C.,
            Stankiewicz,P., Steward,C., Swarbreck,D., Venkataraman,V.,
            Whittaker,C.A., Yang,X., Zimmer,A.R., Bradley,A., Hubbard,T.,
            Birren,B.W., Rogers,J., Lander,E.S. and Nusbaum,C.
  TITLE     DNA sequence of human chromosome 17 and analysis of rearrangement
            in the human lineage
  JOURNAL   Nature 440 (7087), 1045-1049 (2006)
   PUBMED   16625196
REFERENCE   3  (bases 1 to 18111)
  CONSRTM   International Human Genome Sequencing Consortium
  TITLE     Finishing the euchromatic sequence of the human genome
  JOURNAL   Nature 431 (7011), 931-945 (2004)
   PUBMED   15496913
REFERENCE   4  (bases 1 to 18111)
  AUTHORS   Lander,E.S., Linton,L.M., Birren,B., Nusbaum,C., Zody,M.C.,
            Baldwin,J., Devon,K., Dewar,K., Doyle,M., FitzHugh,W., Funke,R.,
            Gage,D., Harris,K., Heaford,A., Howland,J., Kann,L., Lehoczky,J.,
            LeVine,R., McEwan,P., McKernan,K., Meldrim,J., Mesirov,J.P.,
            Miranda,C., Morris,W., Naylor,J., Raymond,C., Rosetti,M.,
            Santos,R., Sheridan,A., Sougnez,C., Stange-Thomann,N.,
            Stojanovic,N., Subramanian,A., Wyman,D., Rogers,J., Sulston,J.,
            Ainscough,R., Beck,S., Bentley,D., Burton,J., Clee,C., Carter,N.,
            Coulson,A., Deadman,R., Deloukas,P., Dunham,A., Dunham,I.,
            Durbin,R., French,L., Grafham,D., Gregory,S., Hubbard,T.,
            Humphray,S., Hunt,A., Jones,M., Lloyd,C., McMurray,A., Matthews,L.,
            Mercer,S., Milne,S., Mullikin,J.C., Mungall,A., Plumb,R., Ross,M.,
            Shownkeen,R., Sims,S., Waterston,R.H., Wilson,R.K., Hillier,L.W.,
            McPherson,J.D., Marra,M.A., Mardis,E.R., Fulton,L.A.,
            Chinwalla,A.T., Pepin,K.H., Gish,W.R., Chissoe,S.L., Wendl,M.C.,
            Delehaunty,K.D., Miner,T.L., Delehaunty,A., Kramer,J.B., Cook,L.L.,
            Fulton,R.S., Johnson,D.L., Minx,P.J., Clifton,S.W., Hawkins,T.,
            Branscomb,E., Predki,P., Richardson,P., Wenning,S., Slezak,T.,
            Doggett,N., Cheng,J.F., Olsen,A., Lucas,S., Elkin,C.,
            Uberbacher,E., Frazier,M., Gibbs,R.A., Muzny,D.M., Scherer,S.E.,
            Bouck,J.B., Sodergren,E.J., Worley,K.C., Rives,C.M., Gorrell,J.H.,
            Metzker,M.L., Naylor,S.L., Kucherlapati,R.S., Nelson,D.L.,
            Weinstock,G.M., Sakaki,Y., Fujiyama,A., Hattori,M., Yada,T.,
            Toyoda,A., Itoh,T., Kawagoe,C., Watanabe,H., Totoki,Y., Taylor,T.,
            Weissenbach,J., Heilig,R., Saurin,W., Artiguenave,F., Brottier,P.,
            Bruls,T., Pelletier,E., Robert,C., Wincker,P., Smith,D.R.,
            Doucette-Stamm,L., Rubenfield,M., Weinstock,K., Lee,H.M.,
            Dubois,J., Rosenthal,A., Platzer,M., Nyakatura,G., Taudien,S.,
            Rump,A., Yang,H., Yu,J., Wang,J., Huang,G., Gu,J., Hood,L.,
            Rowen,L., Madan,A., Qin,S., Davis,R.W., Federspiel,N.A.,
            Abola,A.P., Proctor,M.J., Myers,R.M., Schmutz,J., Dickson,M.,
            Grimwood,J., Cox,D.R., Olson,M.V., Kaul,R., Raymond,C., Shimizu,N.,
            Kawasaki,K., Minoshima,S., Evans,G.A., Athanasiou,M., Schultz,R.,
            Roe,B.A., Chen,F., Pan,H., Ramser,J., Lehrach,H., Reinhardt,R.,
            McCombie,W.R., de la Bastide,M., Dedhia,N., Blocker,H.,
            Hornischer,K., Nordsiek,G., Agarwala,R., Aravind,L., Bailey,J.A.,
            Bateman,A., Batzoglou,S., Birney,E., Bork,P., Brown,D.G.,
            Burge,C.B., Cerutti,L., Chen,H.C., Church,D., Clamp,M.,
            Copley,R.R., Doerks,T., Eddy,S.R., Eichler,E.E., Furey,T.S.,
            Galagan,J., Gilbert,J.G., Harmon,C., Hayashizaki,Y., Haussler,D.,
            Hermjakob,H., Hokamp,K., Jang,W., Johnson,L.S., Jones,T.A.,
            Kasif,S., Kaspryzk,A., Kennedy,S., Kent,W.J., Kitts,P.,
            Koonin,E.V., Korf,I., Kulp,D., Lancet,D., Lowe,T.M., McLysaght,A.,
            Mikkelsen,T., Moran,J.V., Mulder,N., Pollara,V.J., Ponting,C.P.,
            Schuler,G., Schultz,J., Slater,G., Smit,A.F., Stupka,E.,
            Szustakowski,J., Thierry-Mieg,D., Thierry-Mieg,J., Wagner,L.,
            Wallis,J., Wheeler,R., Williams,A., Wolf,Y.I., Wolfe,K.H.,
            Yang,S.P., Yeh,R.F., Collins,F., Guyer,M.S., Peterson,J.,
            Felsenfeld,A., Wetterstrand,K.A., Patrinos,A., Morgan,M.J., de
            Jong,P., Catanese,J.J., Osoegawa,K., Shizuya,H., Choi,S. and
            Chen,Y.J.
  CONSRTM   International Human Genome Sequencing Consortium
  TITLE     Initial sequencing and analysis of the human genome
  JOURNAL   Nature 409 (6822), 860-921 (2001)
   PUBMED   11237011
  REMARK    Erratum:[Nature 2001 Aug 2;412(6846):565]
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            CM000679.2.
            
            On Feb 3, 2014 this sequence version replaced NC_000017.10.
            Assembly Name: GRCh38.p14 Primary Assembly
            The DNA sequence is composed of genomic sequence, primarily
            finished clones that were sequenced as part of the Human Genome
            Project. PCR products and WGS shotgun sequence have been added
            where necessary to fill gaps or correct errors. All such additions
            are manually curated by GRC staff. For more information see:
            https://genomereference.org.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2025_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.4
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/01/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18111
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..18111
                     /gene="HGS"
                     /gene_synonym="HRS"
                     /note="hepatocyte growth factor-regulated tyrosine kinase
                     substrate; Derived by automated computational analysis
                     using gene prediction method: BestRefSeq."
                     /db_xref="GeneID:9146"
                     /db_xref="HGNC:HGNC:4897"
                     /db_xref="MIM:604375"
     mRNA            join(1..93,1595..1679,2302..2377,2993..3085,4694..4817,
                     6172..6224,6664..6732,7437..7561,9493..9571,9644..9742,
                     9860..9955,10805..10843,10914..11057,11154..11213,
                     11776..11989,12347..12519,12597..12737,12814..12988,
                     16457..16590,16685..16804,17035..17121,17498..18111)
                     /gene="HGS"
                     /gene_synonym="HRS"
                     /product="hepatocyte growth factor-regulated tyrosine
                     kinase substrate"
                     /note="Derived by automated computational analysis using
                     gene prediction method: BestRefSeq."
                     /transcript_id="NM_004712.5"
                     /db_xref="Ensembl:ENST00000329138.9"
                     /db_xref="GeneID:9146"
                     /db_xref="HGNC:HGNC:4897"
                     /db_xref="MIM:604375"
     CDS             join(57..93,1595..1679,2302..2377,2993..3085,4694..4817,
                     6172..6224,6664..6732,7437..7561,9493..9571,9644..9742,
                     9860..9955,10805..10843,10914..11057,11154..11213,
                     11776..11989,12347..12519,12597..12737,12814..12988,
                     16457..16590,16685..16804,17035..17121,17498..17608)
                     /gene="HGS"
                     /gene_synonym="HRS"
                     /note="Derived by automated computational analysis using
                     gene prediction method: BestRefSeq."
                     /codon_start=1
                     /product="hepatocyte growth factor-regulated tyrosine
                     kinase substrate"
                     /protein_id="NP_004703.1"
                     /db_xref="CCDS:CCDS11784.1"
                     /db_xref="Ensembl:ENSP00000331201.4"
                     /db_xref="GeneID:9146"
                     /db_xref="HGNC:HGNC:4897"
                     /db_xref="MIM:604375"
                     /translation="MGRGSGTFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKY
                     AVNSIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEV
                     NVRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAAERAPDW
                     VDAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQ
                     LNRKAEGKATSTTELPPEYLTSPLSQQSQLPPKRDETALQEEEELQLALALSQSEAEE
                     KERLRQKSTYTSYPKAEPMPSASSAPPASSLYSSPVNSSAPLAEDIDPELARYLNRNY
                     WEKKQEEARKSPTPSAPVPLTEPAAQPGEGHAAPTNVVENPLPETDSQPIPPSGGPFS
                     EPQFHNGESEESHEQFLKALQNAVTTFVNRMKSNHMRGRSITNDSAVLSLFQSINGMH
                     PQLLELLNQLDERRLYYEGLQDKLAQIRDARGALSALREEHREKLRRAAEEAERQRQI
                     QLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQMRAQMPAFPLP
                     YAQLQAMPAAGGVLYQPSGPASFPSTFSPAGSVEGSPMHGVYMSQPAPAAGPYPSMPS
                     TAADPSMVSAYMYPAGATGAQAAPQAQAGPTASPAYSSYQPTPTAGYQNVASQAPQSL
                     PAISQPPQSSTMGYMGSQSVSMGYQPYNMQNLMTTLPSQDASLPPQQPYIAGQQPMYQ
                     QMAPSGGPPQQQPPVAQQPQAQGPPAQGSEAQLISFD"
     misc_feature    7518..7520
                     /gene="HGS"
                     /gene_synonym="HRS"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0007744|PubMed:19608861; propagated from
                     UniProtKB/Swiss-Prot (O14964.1); acetylation site"
     misc_feature    7545..7547
                     /gene="HGS"
                     /gene_synonym="HRS"
                     /note="Phosphotyrosine.
                     /evidence=ECO:0007744|PubMed:15592455; propagated from
                     UniProtKB/Swiss-Prot (O14964.1); phosphorylation site"
     misc_feature    join(9497..9571,9644..9742,9860..9955,10805..10825)
                     /gene="HGS"
                     /gene_synonym="HRS"
                     /note="propagated from UniProtKB/Swiss-Prot (O14964.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    join(9503..9571,9644..9742,9860..9955,10805..10843,
                     10914..11057,11154..11213,11776..11989,12347..12519,
                     12597..12659)
                     /gene="HGS"
                     /gene_synonym="HRS"
                     /note="propagated from UniProtKB/Swiss-Prot (O14964.1);
                     Region: Interaction with SNX1. /evidence=ECO:0000250"
     misc_feature    9941..9943
                     /gene="HGS"
                     /gene_synonym="HRS"
                     /note="Phosphotyrosine.
                     /evidence=ECO:0000250|UniProtKB:Q99LI8; propagated from
                     UniProtKB/Swiss-Prot (O14964.1); phosphorylation site"
     misc_feature    10923..10925
                     /gene="HGS"
                     /gene_synonym="HRS"
                     /note="Phosphotyrosine.
                     /evidence=ECO:0000250|UniProtKB:Q99LI8; propagated from
                     UniProtKB/Swiss-Prot (O14964.1); phosphorylation site"
     misc_feature    10938..10940
                     /gene="HGS"
                     /gene_synonym="HRS"
                     /note="Phosphotyrosine.
                     /evidence=ECO:0000250|UniProtKB:Q99LI8; propagated from
                     UniProtKB/Swiss-Prot (O14964.1); phosphorylation site"
     misc_feature    join(10950..11057,11154..11213,11776..11817)
                     /gene="HGS"
                     /gene_synonym="HRS"
                     /note="propagated from UniProtKB/Swiss-Prot (O14964.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    join(11929..11989,12347..12519,12597..12659)
                     /gene="HGS"
                     /gene_synonym="HRS"
                     /note="propagated from UniProtKB/Swiss-Prot (O14964.1);
                     Region: Interaction with SNAP25 and TRAK2.
                     /evidence=ECO:0000250"
     misc_feature    join(11956..11989,12347..12519,12597..12737,12814..12822)
                     /gene="HGS"
                     /gene_synonym="HRS"
                     /note="propagated from UniProtKB/Swiss-Prot (O14964.1);
                     Region: Interaction with STAM.
                     /evidence=ECO:0000250|UniProtKB:Q99LI8"
     misc_feature    join(12391..12519,12597..12737,12814..12988,16457..16590,
                     16685..16804,17035..17121,17498..17605)
                     /gene="HGS"
                     /gene_synonym="HRS"
                     /note="propagated from UniProtKB/Swiss-Prot (O14964.1);
                     Region: Interaction with NF2.
                     /evidence=ECO:0000269|PubMed:10861283"
     misc_feature    join(17050..17121,17498..17605)
                     /gene="HGS"
                     /gene_synonym="HRS"
                     /note="propagated from UniProtKB/Swiss-Prot (O14964.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    132..231
                     /standard_name="ATAC-STARR-seq lymphoblastoid silent
                     region 9145"
                     /note="Region: biological region; Derived by automated
                     computational analysis using gene prediction method:
                     RefSeqFE."
                     /db_xref="GeneID:130061964"
     regulatory      132..231
                     /regulatory_class="silencer"
                     /experiment="EXISTENCE:reporter gene assay evidence
                     [ECO:0000049][PMID:35858748]"
                     /note="silent region_9145"
                     /function="represses an Ori minimal core promoter by
                     ATAC-STARR-seq in GM12878 lymphoblastoid cells
                     {active_cell/tissue: GM12878}"
                     /db_xref="GeneID:130061964"
     misc_feature    8666..8851
                     /standard_name="ReSE screen-validated silencer
                     GRCh37_chr17:79659706-79659891"
                     /note="Region: biological region; Derived by automated
                     computational analysis using gene prediction method:
                     RefSeqFE."
                     /db_xref="GeneID:129664176"
     regulatory      8666..8851
                     /regulatory_class="silencer"
                     /experiment="EXISTENCE:reporter gene assay evidence
                     [ECO:0000049][PMID:32094911]"
                     /note="fragment chr17:79659706-79659891 (GRCh37/hg19
                     assembly coordinates)"
                     /function="represses an EF-1alpha promoter that drives an
                     FKBP-Casp9 reporter gene in an ReSE screen in K562
                     erythroleukemia cells {active_cell/tissue: K562}"
                     /db_xref="GeneID:129664176"
     gene            9747..9859
                     /gene="MIR6786"
                     /gene_synonym="hsa-mir-6786"
                     /note="microRNA 6786; Derived by automated computational
                     analysis using gene prediction method: BestRefSeq."
                     /db_xref="GeneID:102465471"
                     /db_xref="HGNC:HGNC:49970"
                     /db_xref="miRBase:MI0022631"
     precursor_RNA   9747..9859
                     /gene="MIR6786"
                     /gene_synonym="hsa-mir-6786"
                     /product="microRNA 6786"
                     /note="Derived by automated computational analysis using
                     gene prediction method: BestRefSeq."
                     /transcript_id="NR_106844.1"
                     /db_xref="GeneID:102465471"
                     /db_xref="HGNC:HGNC:49970"
                     /db_xref="miRBase:MI0022631"
     ncRNA           9799..9819
                     /ncRNA_class="miRNA"
                     /gene="MIR6786"
                     /gene_synonym="hsa-mir-6786"
                     /product="hsa-miR-6786-5p"
                     /note="Derived by automated computational analysis using
                     gene prediction method: BestRefSeq."
                     /db_xref="GeneID:102465471"
                     /db_xref="miRBase:MIMAT0027472"
                     /db_xref="HGNC:HGNC:49970"
                     /db_xref="miRBase:MI0022631"
     ncRNA           9834..9856
                     /ncRNA_class="miRNA"
                     /gene="MIR6786"
                     /gene_synonym="hsa-mir-6786"
                     /product="hsa-miR-6786-3p"
                     /note="Derived by automated computational analysis using
                     gene prediction method: BestRefSeq."
                     /db_xref="GeneID:102465471"
                     /db_xref="miRBase:MIMAT0027473"
                     /db_xref="HGNC:HGNC:49970"
                     /db_xref="miRBase:MI0022631"
     misc_feature    16424..17028
                     /standard_name="H3K4me1 hESC enhancer
                     GRCh37_chr17:79667464-79668068"
                     /note="Region: biological region; Derived by automated
                     computational analysis using gene prediction method:
                     RefSeqFE."
                     /db_xref="GeneID:127888489"
     regulatory      16424..17028
                     /regulatory_class="enhancer"
                     /experiment="EXISTENCE:reporter gene assay evidence
                     [ECO:0000049][PMID:30033119]"
                     /note="H3K4me1 hESC enhancer chr17:79667464-79668068
                     (GRCh37/hg19 assembly coordinates)"
                     /function="activates a minimal SCP1, AML or CMV promoter
                     by ChIP-STARR-seq in naive H9 embryonic stem cells
                     {active_cell/tissue: H9 hESC(naive)}"
                     /db_xref="GeneID:127888489"
     misc_feature    17029..17632
                     /standard_name="H3K4me1 hESC enhancer
                     GRCh37_chr17:79668069-79668672"
                     /note="Region: biological region; Derived by automated
                     computational analysis using gene prediction method:
                     RefSeqFE."
                     /db_xref="GeneID:127888490"
     regulatory      17029..17632
                     /regulatory_class="enhancer"
                     /experiment="EXISTENCE:reporter gene assay evidence
                     [ECO:0000049][PMID:30033119]"
                     /note="H3K4me1 hESC enhancer chr17:79668069-79668672
                     (GRCh37/hg19 assembly coordinates)"
                     /function="activates a minimal SCP1, AML or CMV promoter
                     by ChIP-STARR-seq in naive and primed H9 embryonic stem
                     cells {active_cell/tissue: H9 hESC(naive and primed)}"
                     /db_xref="GeneID:127888490"
ORIGIN      
        1 gcgccagctc gtagcagggg agcgcccgcg gcgtcgggtt tgggctggag gtcgccatgg
       61 ggcgaggcag cggcaccttc gagcgtctcc taggtaacgc gtccccaccc gacggctcgg
      121 ccttggtcag cccgcagcct ccgcccggcg ctgagtcagc gcggccccga gggcccgagg
      181 ggcgcggacc ggccgccctg cccgcctctc cccggcccgc tgtcctcccg ggttcggagc
      241 cgccgatcct ggaccctcgg cgcggccgtg gggtcggcgt ccgtcgggcg ttggcaaatg
      301 gggctctgcg agggtccgcg cagggcgcca ggggcgctcg gcgacctcgc tcctccgcgg
      361 gcccgggcat tcggccgatt tcctcttgac cgacgagcac ccggccgagt gggccacaag
      421 gcctgagtca tgaaagtggg tgactcagtc ggatgttagg ctcgcacttg ggcttctgac
      481 ccaaaacact gggcctcgaa gggtggagcc ggcagtgttc tctctgggac cttcgagctc
      541 tcttgggggc tgcgggtccc agacccacct tttgttccca cactggcttc gggaagtgcc
      601 taatggttta ggaaggcgtt ttctcacgtt tttggaggtg aaagctgatc ctatctgagc
      661 ctcctggaat tgacgcgttt tgggagggaa acgaatgttg atgtgcacgt gcccagcagc
      721 acgtggaaaa tgcgtctaat gtttgggggt aggagcttgg gtggtcgaat gggctgccca
      781 agcttgcctt tttgtcaagt agggttttca aggagacttc aagtgagaca ccttccttgc
      841 caagggaacc agcaagcaga ctgagtatct cagccacaca ggtagttcag tgcttcaggg
      901 atgaatccag aggttaacta ctgaatcagt atagaaagtg gacgtggctt ggcttgttag
      961 atcgtttctg tatccgggaa aggcgatgtg ggcagagctg gagctgcccc cccagagggg
     1021 ccagttgttg gagacagcag tgatgtggta tgatgacagg tatgctggcg agtcctcctt
     1081 ggagccccgt tctgccctta tttccaaagc acttggcttg gagcaagggg cctggagtct
     1141 acactgcagg cctctctagc ccttgcccaa gctaaggtcc cattgaaacc gggagcatct
     1201 gggcgaacgg ggactccaag ggacgggtga tagggttctt tgttgagaag cagccgagcc
     1261 tgatgtttaa gagtgaatca gcctctgtct ctggtgagct gtgtgactca cggcagtgcc
     1321 ctcgcctctc tgctgagtgt ctttacctcg ctcgcgggtt gtgggagggc ttggaccagc
     1381 acctggtgtg ctcttacgct gtttgctgct tccctgggga ggatggcact tccctgccca
     1441 tcagcacgct caggaggatt ctgtcatgct ttttcatttg gtccaaatgt ctaaagggga
     1501 aggagagagt cccccccagc tgctgccaag ctggggtgct gcacggggcg tccagcagga
     1561 taacccctcc ctttcatggc attttctctc tcagacaagg cgaccagcca gctcctgttg
     1621 gagacagatt gggagtccat tttgcagatc tgcgacctga tccgccaagg ggacacacag
     1681 tgagttagcg gggcctgtgc cctgatgcgg aggagcagcc gtgcactaag ctgggctcgc
     1741 ttggtgcccg ttgggtctcc acgacgtagc tgaccgtgtt aggctcttat gtggagaact
     1801 gcatgggcta catgctagga ttttttgaca tcttggagga ttaaggggtt ttctctgtac
     1861 agcttgcaga tacctggtta tgtttgtatt tgcttcgggg ttctcaaaga ctaagatggc
     1921 agacagactt ttttttttaa gacggggcct tgctttgtca cccaggctga agtgcagtgg
     1981 cgtgatctca gctcactgca gcccctgcct cccaagctca aacgatcgtc ccacctcaac
     2041 ctcctgagta gctgggacta caggcattca ccatcacgcc cggctgattt tttgtatttt
     2101 ggtagagatg ggtttttgcc gtaatgcaca ggctggtctc agactcctgg gctcaagcaa
     2161 tcctcctgcc ttggcctccc aaagcactgg gattacaggc gtgagccact gcacctggca
     2221 gcagatgagc ttttctcatc ttagttgctg agactatttt tttcccgttt ttctctgctt
     2281 ttatcaatgt ttccttttca gagcaaaata tgctgtgaat tccatcaaga agaaagtcaa
     2341 cgacaagaac ccacacgtcg ccttgtatgc cctggaggta agcagacccc cgtgcctcag
     2401 tggcccccag ggtccctacc ccctactagt cacgacagca tgagaagagt ttgtcctgtg
     2461 gccttgccca cctccctggg catacatcaa gcaggagagt ttccactcag ccttgagtgc
     2521 ctgtgtgaac agtgccacct aggagagggt cacgctgagg gagagacagg agatagggga
     2581 gggagtgggc accacttctt cagccggtcc tgcgtgagta aacaccagaa ggcggatgtc
     2641 attgctgtgc ttggcagtga gacttggcgt cacggagcgg tgctgtgcag gctgctgagt
     2701 ctcagatgtg ggttccccac tggcctgacg ggcctgttga agggctgctg tcccaccggg
     2761 ttccccaccg gccactgacg ggcctgtcga agggctctgc tgtcccaccg ggttcccctc
     2821 cggccactga cgggcctgtc gaagggctct gctgtcccac cgggttcccc accggccact
     2881 gacgggcctg tcgaagggct ctgctgtccc acagggaggt gggtctgtcc gggaggagga
     2941 ggggccctgc cctgaccact ggcccaaccc ttcccttcct gggcatctgc aggtcatgga
     3001 atctgtggta aagaactgtg gccagacagt tcatgatgag gtggccaaca agcagaccat
     3061 ggaggagctg aaggacctgc tgaaggtggg tgagacgggg gcatgcgggt ggccacccag
     3121 gctggcacct ttgcttctcc gggtgtttac tgggcactga tgacagaaca gcaccaggtg
     3181 tggcggaaaa tgtgcaggtg cagatcggtg gtccctgcac tgcgcaagct cgcactcatg
     3241 agtcggagag acagggccgt gagccccaat ccagggaggt cagggtttag caggagccgg
     3301 cctggggtgc tgtgtctgga ggaccaaggt gacagcgacc ctggggcctg ggggaagctt
     3361 ccgggaggca gggcttgggc acctgctgtc ttagggaagg tgagtagatg ccactgggtg
     3421 ggcagggcag gtggtggcta tcgtgtgtga gagtggctgt ggtccggagg gcaggctggc
     3481 cacatcccac aggcaggggc ctgggagggc tctgagcggg ggcttgtaag atcggatgtg
     3541 tctggcgggg ataagagctg ttttggagag cgagggcttc atgctttcct gggcagagga
     3601 ggaaaagccc tccagatccc caggagattg tgccggggac atctgcaggg attgtgctgg
     3661 ggacacctgc agggactgtg atgtggactg tgatgcagtg gggatgctgt tgcaggtgtc
     3721 aaggagaaag agtgtcccat gtagtcaggc tgctcccctt ctgtcccaac ctgtgggcca
     3781 gacctgggtc tcataggaga ctccctggac tcacacagct gagaacctgc ccggggatcc
     3841 cggtggacag ccaggcctct caaaggccct cactggccac tttggctggc ttcctgtccc
     3901 gtcctgtcct ggctgagagg cggaaggtgc cggagtctgg ccctgcccga ccctggtgct
     3961 cctgagctcc ttcagtcagg ctgcagatcc tgagccggtt cgctcctctg gggtgaggca
     4021 gggctgtgaa gggaaggcgc cgctgaggat gcagaggggt tctggaaagg agcttaggct
     4081 gaggtgcaag tgccccggag cctgcttgca gcagcctctg atcgcacgcc gtcctgcacg
     4141 tcacaccggg acggcgtccc cgagagggcc gtagacgcga ggccaggctg cgctctaacc
     4201 gggggagagg atggctgcag ggggtctgga gcccgctctg aatttggagg catttctgga
     4261 gcggctgccc cccgcgtctc cccggctgtg actggaagga ggggcgtggc cagagccccg
     4321 cagtacccct gtgttctcag ccccaacacc acgctgccac cgtcaggcct gccgggtcct
     4381 gcctgttgga ggctgacggg aaccggggat cctggggtgg gcaggtcccg tggggaaagg
     4441 gagagacaga tggtcagggg cacagagacg cggcgttgtt tggctccagc aagtagaggc
     4501 aggcgtgagg tttgaactca gggtctggga acaggttggt gcatggcccc cacgccccac
     4561 tcggggggcc ctccctggcc tctgtgtcag ccccatctgc tcagaggctg aggtctgcca
     4621 gctgcttcct cacaccgagg cctctggcgc ctggagtgtc ctgcgaccct cacccccttc
     4681 tccctgcctg cagagacaag tggaggtaaa cgtccgtaac aagatcctgt acctgatcca
     4741 ggcctgggcg catgccttcc ggaacgagcc caagtacaag gtggtccagg acacctacca
     4801 gatcatgaag gtggagggtg agtcaggact gaggttggga ccaggttgag gcttggaact
     4861 gctgggcagt caggctcaac gggcacagtg gcgaggggcc tgggaagatg ggttgttccc
     4921 tgtgttggga gggaggaggg cggtggcctg gagccaggga agaccgtgca tgtgagggcg
     4981 ggttcagacc ggctcctgcc tttctggacc cacggcccac gggcaggggc aggcagtgat
     5041 ggcagacaac acacaggtga aaaggcagca gacagcctgt ttcagagtgg caggactcct
     5101 gggggccggg ttgggctgtg cagtcaggga aggcctctga aggagctgtc ccaagtgtcg
     5161 agactggaac agaagccaga gccggcgtga gcaggcaggc agcacccgtg ggcagacact
     5221 cagggttgag gccccagggc agaaaggtgg ccagcgtgcc agaggagagt gcagccgggc
     5281 ctgtgcgccg agggcctcca ggctgttggg ctggagttca gggttgctgt cagcgcagca
     5341 ggaggcctct ggtgggtttt cgtctaggtc gtggctgcca aggtgtgttt cttaagggtc
     5401 cctctcggcc attgtggccg tggagaacta ggggattgtg tagagagagg tgggggcttc
     5461 aggatgcatt tgggagtctt ggctggtgct cagggcccac tcagtgagag agaggtgggc
     5521 atggctgctc acatctgtgc gggttctctg tggccctgag tctgctgaag acgaggctga
     5581 gagcgtgggg aatggggcag gctccagggg tggtgcgtcc ccgctgcagg agttggacgc
     5641 ttgccctgtg gctgcagggt gggcaggacc agtgtggaga acacgggaag aacgcagggg
     5701 gcgctgcacg agctgccttg gaccctcaac tttggggtgg tggatgctgg tggtctgtgc
     5761 tcctgtctcc ttcctggggt gggagctctc ctggattttt tctggggtcg tgtgtcaaga
     5821 atagctcaag gtcttgtcct caggatcagt gggagccctg gccagagagc agagggtgag
     5881 ggagccactc agcaggcggg gccacgcagg ggcctcatgc cctgatggag tgggagcagt
     5941 gtctcaggaa gagggcagca gggcctggct cttgtctccc gccacagtga ggacagaggc
     6001 cccatgggga cacccaatct tgggggcagg aggctgtctc ggtgccccca gacaccttca
     6061 cttgggtgca cggtcactgc tgcgttgcag ctgccgagag tgaggaaggg gctcccggaa
     6121 gtcttgcagg ccaggtggga gcaggcagtg actatggctt catctctcca gggcacgtct
     6181 ttccagaatt caaagagagc gatgccatgt ttgctgccga gagagtgagt gtgggcggcc
     6241 gccaggggtt ctggagtcgg gctgctcagg aagcgtgaag gggagtgctg ggagcccggc
     6301 ttgtttgagg gttggtggct gagctctcgt ctgtctggga cctgaggatg cctgtgtgtc
     6361 ctgggcggag gcgtagcagc tgtctctgca gggcgaggtg gagacgtggc ttgagggcct
     6421 ttagagtggc tagggggctc gggaaaggaa aacaagcacc tttgatgagg aaggaagtcc
     6481 cttcctcagg cctcggcagc ttcaccccag gccacgccgc tgggaagggc cgcccggggc
     6541 attgctctcg ctcgtgctgg ggtcctctct gggtccgttg ccttctgtgg ggcaggggag
     6601 gctctgtgcc tctggggctg gtggggcggg aagcgtgtgg tcctgactgc tgcccctcct
     6661 caggccccag actgggtgga cgctgaggaa tgccaccgct gcagggtgca gttcggggtg
     6721 atgacccgta aggtgagttc ccacctgggg ggctctacag ccccggccag acaccaggtc
     6781 ccctgccgtg cacaaggcca ccgtccctgc tgggcctttc cttcctggtg ggtggttcag
     6841 gaggtgagtg cagctcgcag cgggtggcag tgtggcgtca ggagggggac agtgagggcc
     6901 cacgtaaggg cctgatgcca ctgcctgggc cgggcccagc ctcactctgg aattataatg
     6961 ttttaaacct agggctacag gccttgccac agtcactctg ctgcttgcca gggccgtggg
     7021 gcccccttct ctttgtggct tagcccatct ggattcttac cctcgaggca tcttcacatc
     7081 aaaaccccct ccaggctggc aaccggcagt gcttggggtt tggggtgtca gcagcttcca
     7141 gcacccactg cactcacaaa agctcttgtt ttatcagcag aattgatgtg tattttttcc
     7201 ttgcccttac ttttaactta ccttattttc cccaaaacgg tggctggcgt tgagactccc
     7261 gggagcatgt ccaggttccc cggccttagg gtcttcccag gcacttgttc tgcttgtccc
     7321 ttgccttccc ccacctgtga ggcccagctt cggcatcgta cggggtggtt ctgggccggg
     7381 tggcgcatca gggtccccca gtgcctgtga ccaggcccgc ccgccccatc ttacagcacc
     7441 actgccgggc gtgtgggcag atattctgtg gaaagtgttc ttccaagtac tccaccatcc
     7501 ccaagtttgg catcgagaag gaggtgcgcg tgtgtgagcc ctgctacgag cagctgaaca
     7561 ggtgagtccc cgccccccat ttgggctgca ggtggggcag gctctccagg ctgggttttc
     7621 tgtccctctt ggccatggtg cctgaggcct gcagacccca gaggaccctc acagcacagc
     7681 agctggaagg tcaagggaaa cccagggtgg ccgcatgccc tcggaccctg ccccacacta
     7741 gggcaggtgg gtgtgagaga cagggcgccg cggctccagg gaccgaggct gccccgacaa
     7801 acctgttgct tgggtttggg tttgggtttg tttgcatttc aactttcgga ataaaactta
     7861 cagaaaagtt gcaagagtag cacagagaag ctgcggggcc gcggccagtg cctcagcggt
     7921 gggaacctgc ggggccgcgg ccggtgcctc ggcggtcggt gttttgtcgc agagtttact
     7981 ctgcctcccc tctcctgcgc gtgcgtgtgt tcacacaggt tttattttga atttgcatga
     8041 gtgcagatgt catgcccctt ggcactcaga tcttcgcctg tgatctctga gagggacagt
     8101 gctctcatgg ccacagcagt cactcgggac tgcgctgcca cccagtgctg gcttctgctc
     8161 tgtggtccac gttccatttc tgccgtggtc ccagcagcgt cgctgtgggt ctggcctggg
     8221 ttgcgtgtgt ttcgtatgtg ggccgtgctc cctgcttggt tcccttttcc tggaacgtgt
     8281 cactgcctcc ctgtctcgct ccgtggacat ttctgggagg tcaggccgtg gccacctggc
     8341 cccctgttca ggtctgaggc tcccacctgc ttaggttcgg gaagctcagg agtgaggcca
     8401 tgccctcctc aggacatccc atccaagcca gccatgtccg gtgatgggcc gctgcccgga
     8461 aagttccttt tccttcttgt aactgagaag aacttgcctt gagccacgtc aagtcccgtc
     8521 cgtcgcagcc actgcccaca agcgtgagtc tgctgtgagc cagcggctcc atggcagggc
     8581 atcccagcgc cattcctgcc ttcacacaca cttgctgccg tttccctgtg ctgggggctg
     8641 tgcaggtctg cctcggtgtg gacttttctc ttaggaaaga gccccaggtc ggccgagcac
     8701 ggtggctcat gcctgtaatc ccagcacttt gggaggctga ggcgggcaga tcacgaggcc
     8761 aagagatcaa gacaatcctg gccaacatgg tgaaatcccg tctctacttt ttaagtattt
     8821 tatacttaaa atttttgtat tttatacaaa aattagcggg cttggtggca gatgcctgta
     8881 gtcccagcta ctcgggaggc tgaggcagga aaatcacttg aacctgagag gcggagattg
     8941 cagtgagcca agatggcgcc actgcattcc agcctgggcg acagagcaag actctatctc
     9001 aaataaaaaa aaaagaaaag agccccaggt caaaggtcag cgtgcgtggt tggaaattgc
     9061 gaccatgctg tgagcctgcg gcccttggac tgcctggggc gccccggaag agcttactgg
     9121 gcatgacagt cactgacctg tttgcccctt cttgggtggg gcccgtccca cagtggcggt
     9181 gctgtgtttg gtttcccgag tgccgtagga aggtcttcgc aggccgggct ggtgtcctga
     9241 atgtccattt tcaggagagg aactggggct taccctgagg gactcacccg agcccttgtg
     9301 gctggtgtga tgccctcgag tcctgccctg ctctgctctg gagtgtggcc attcggacac
     9361 ctgtggctgt ggaaccactg tcctcactct gtggggacac ttagaggagc ccgcagaggt
     9421 gtggttgaga gctttggcgg gggcagggcg gtgtcagcgc atggtgacct gcagcattcc
     9481 ttgtgcccac aggaaagcgg agggaaaggc cacttccacc actgagctgc cccccgagta
     9541 cctgaccagc cccctgtctc agcagtccca ggtactcagc cccctccgtc ccgtgggcac
     9601 ctcttccccg gcgccccccc tcaccctccc cgcttgtcct cagctgcccc ccaagaggga
     9661 cgagacggcc ctgcaggagg aggaggagct gcagctggcc ctggcgctgt cacagtcaga
     9721 ggcggaggag aaggagaggc tggtaagccg ggtggggcgg ggcggcctca ggaggggccc
     9781 agctcccctg gatgtgctgc ggtggggccg gaggggcgtc acgtgcaccc aagtgacgcc
     9841 ccttctgatt ctgcctcaga gacagaagtc cacgtacact tcgtacccca aggcggagcc
     9901 catgccctcg gcctcctcag cgccccccgc cagcagcctg tactcttcac ctgtggtgag
     9961 cggcccttgg gctggagctc cctctcctgg aaggcagtag ggttgatggg ggacgcgggt
    10021 ccctgagctg atttagtcag gttggtgggg gatgcgggtc cccgggcttc ccagagagga
    10081 cagccccagc acacgggcgg acatcagggc agagccccac ggctccaggc acccgttgct
    10141 cctggtccct ggttcggccc ttgggactga ggacatggga caggctgtgg gggaggcgcc
    10201 ttgctggtga gaccccgtct cttccacacc cctcccgccc cacaggaact gaaggacttg
    10261 ctttctgggg catccacgtc acctctccct ggcctcagcc ccgctctcag tagagggtga
    10321 agaggcagcc tgttttgcag ggggttgggt cggggacagc aggttgagaa agtcattttg
    10381 taggttccgt ggagtggcca ggccgctgca ggcccagggg tgcagaacag ccctgcccca
    10441 gtgagccacc ccttcccttc ttcccttcct tccgggctgt cggctggggc cccacacgct
    10501 ggaccgtggg ggctgtccag tgtccacctt gaggccccag ggctggccca gtgccaccct
    10561 gttcctccca tagcaaggtt aggagccttg taggacggca gtgctgtcag cctctgtgga
    10621 gttctaagca tctggaagag gagaaaagat ggctgctcag atgccaggaa ccagaggagg
    10681 gcacggaggg agggcccagg ctgcggctct ggtctccagg atctgtcgca ctggggacat
    10741 ccctgtccct gccgaagcaa ctggctctgt cacctgtgag actcagatgc ccttttctcc
    10801 ccagaactcg tcggcgcctc tggctgagga catcgaccct gaggtaaggc ccagcatggg
    10861 gtgcatcctc tcacggtttc tggccttggg agtgaccccc tcattgcctg cagctcgcac
    10921 ggtatctcaa ccggaactac tgggagaaga agcaggagga ggctcgcaag agccccacgc
    10981 catctgcgcc cgtgcccctg acggagccgg ctgcacagcc tggggaaggg cacgcagccc
    11041 ccaccaacgt ggtggaggtg agggggccac tcccggcatt cctagtggca gggtcccttg
    11101 gaaggggtgg atgcgggaca ggttggaggc cccactcatt ctctctcttc cagaaccccc
    11161 tcccggagac agactctcag cccattcctc cctctggtgg cccctttagt gaggtaagct
    11221 gtggctccct ccacgggcca gggcaaaaca tggcctcctg gcccacagcg ccaggcacat
    11281 ggcacaggtg cctgccctaa ccagagggcc gtgctagagc aagggtgtct gccccagccc
    11341 agccctggcc tgccctgccc tgccctttgt ggcctctccc aatggaaact ctacaccagg
    11401 ctgtggtcca gagctcgggc cactctctgt ggacctaaca tggacctgaa tattccagag
    11461 cagcctagaa ccatcagatg agtccttggc gttgcctggg gcttgtgggc tggttggctg
    11521 tcagagcaca ggtccctgga gagggagctg gcagtggggc cctgagccag ctccgtcctg
    11581 accagggctt gcagctggac aaggaccccg cctccagggc ctcgccttcc tcagctgtag
    11641 aaggggctgc ttgcataagg agcagatgga ctctgctcca ggcttgagta tagctgggtg
    11701 cctccatccc aggccccacc agggaggctg gctggggcgt ggccgcactc atccagaacc
    11761 ctgctctgcc tgcagccaca gttccacaat ggcgagtctg aggagagcca cgagcagttc
    11821 ctgaaggcgc tgcagaacgc cgtcaccacc ttcgtgaacc gcatgaagag taaccacatg
    11881 cggggccgca gcatcaccaa tgactcggcc gtgctctcac tcttccagtc catcaacggc
    11941 atgcacccgc agctgctgga gctgctcaac cagctggacg agcgcaggcg taggtgcccg
    12001 cgccacgggg cctcggctca ggggcagcca ggtgttgtga gcgccatcct gggccagggc
    12061 ctcccctgag ggtgctgagc tcttgtgagt ccttcattgg ggccgtggct tcctccagag
    12121 agtgtcaaca ggaggtggtc tcagtgatga ccatgccctg ccctgccctg ccctgccctg
    12181 ccctgccctg cccaggaccc tctgcctgcc tcccccagag cccagcacct tcagagccct
    12241 ctgcagaagg ttgggcacag ggcggcccat ctgcgtgtcc gttccaccca ggagcttctc
    12301 ggcactgtgc cggagtggtc agggttgctc tgtcatctgc ccacagtgta ctatgagggg
    12361 ctgcaggaca agctggcaca gatccgcgat gcccgggggg cgctgagtgc cctgcgcgaa
    12421 gagcaccggg agaagcttcg ccgggcagcc gaggaggcag agcgccagcg ccagatccag
    12481 ctggcccaga agctggagat aatgcggcag aagaagcagg tgcagtggct gcccagccac
    12541 aggccggggc cggctggggg acctcgcagc ataaccagca tgtttttgcc gcacaggagt
    12601 acctggaggt gcagaggcag ctggccatcc agcgcctgca ggagcaggag aaggagcggc
    12661 agatgcggct ggagcagcag aagcagacgg tccagatgcg cgcgcagatg cccgccttcc
    12721 ccctgcccta cgcccaggca tgtgccatcc tcccgccacc cagaggcttg tgggctgagg
    12781 accaactctc accgctgtct cttttgtccc cagctccagg ccatgcccgc agccggaggt
    12841 gtgctctacc agccctcggg accagccagc ttccccagca ccttcagccc tgccggctcg
    12901 gtggagggct ccccaatgca cggcgtgtac atgagccagc cggcccctgc cgctggcccc
    12961 taccccagca tgcccagcac tgcggctggt aaggacgggt cggggcagag accatgcctt
    13021 ttatccctcg tctttatttt agccgaattt acagaaaagc agtaagaatg gtgcgaaggg
    13081 ttttcccagt tgccccgatg tgaatgttgt ccctgctttt tcctgtttcc atgcaaacgc
    13141 actcacacag gctttcctgc tggagccgtg tttcagtccg tgcgtggcag gtactgccct
    13201 ctcccctgaa tgcgacagcg agcatttcct gaaaccagca ggtgctgggc tgccgatcct
    13261 cgtctgtagc aggctcagcc ctcatggact gtcccagtgg tgtcctgtaa acagcacgcc
    13321 ccctgctgcg tggcatttgc cccccccccc cccgccttta atctagagtg ttccccagtc
    13381 agcttctgtg ttttgtgaca tctactgtcc caagagcact ggcctgtcat tcggcagacc
    13441 gtcctcagct caggtttgtc tggtgtctcc acgcggtgac cataaggctg tgcttttctc
    13501 agagtggcag ccgaggtgac gtgcatcccg tcagtcccat tgctggccgt tcggctgaga
    13561 cggggtctgc caggggtttt cactgtgaag tgactgtttt gccctttaca gatgtctctt
    13621 gggggaggcc ttccaaatac cctgggactc ctcaaggtct agcatttttt gctaatgttg
    13681 cctgtgttta ttacggtgtt tgccaaatag cgccttctaa ttctgctgtt gtctttccac
    13741 tggcgggagg tactcttccc cactctcctg cttatcgtca gtcacagcag cgtggagacg
    13801 tgtttatttt ttctttcaaa ggtgacactc ctctgtcatc actctttatt tttagagtct
    13861 cgctgtcatc caggctggag tgcagtgcca tgatcatggt tcactgcagc ctcgacctcc
    13921 tgggctcaag caatcctccc atctcagcct cttgagtagc tgggactaca ggattgcacc
    13981 accatgcctg gctaattaaa aaaaaaaggg ctgggtgcgg tggctcacgc ctgtagtccc
    14041 agcacattgg gaggctgagg caggtgggtc atgaggtcag gagttcaaga ccagcctgcc
    14101 aggatggtga gaccctgtct ctactaaaca tacaaacatt aggtgggcgt ggtggcacgt
    14161 gcctgtaatc ccagctattc gggaggcaga ggcagagaat gaattgagcc cgggaagtgg
    14221 aggttgcagt gagccgaggt tgcaccacca cactctagcc tgagcaacag agtgaaactc
    14281 catctcaaaa aaaatgtaga aatgaggtct ttctgtgttg cccaagctga cctcaaactc
    14341 ctgacctcga gtgatccgcc cttctcggcc ttccaaagtg ctgggattac aggtgtgagc
    14401 caccgtgccc agccccgtta ctttgatgct caaagtttcc caggtgtggc catgggaggc
    14461 gtcagtggct tctctgttgc gtagggccat tggtttgggt tgctcctgag tttctgttgc
    14521 tagatactct gtgctcgtct tgtatgttct caaccctgga agcagccatt tctccaagga
    14581 gcccttgttc cctttagtgg agggtggtct ggatcttggt tagaagccaa gatcaagatt
    14641 ctgggtgtgc tcacagctct aggttgttag cagacagagc tggaaagtgt gtatgtgaat
    14701 acaagtgcac agttgtgggt gcgtctgtgt atgtgcgaat acatgcgtct ttgtatatga
    14761 taaaaaccgt gagtgcagcc aggtgcggtg gctcatgcct gtaatcccaa cactttggga
    14821 ggccaaggcg cgtggctcac ctgaggtcag gagttggaga ctggcctggc caacatggtg
    14881 aaaccccgtc tactaaaaat acaaaaatta gccaggcgtg atggtgcaca cctgtaatcc
    14941 cagctacttg ggaggctgag gcaagagaat cactggaacc tgggaggtgg aacttgcagt
    15001 gagccaagat catgccattg ccctccagcc tgggtgacag agcgagactc cgtctcaaaa
    15061 aaaaaaaaaa aatccatgag ttaattccag tacttgcaat tttaatccaa tagcacagtt
    15121 ttcttttgca ttgttttcaa tatactcaat tgctcagccc tagaatacac aaaaagtagt
    15181 tttaagaatg ctaacctggc ccactgtgga gacgatgcct cctaactgga gtgtaacatt
    15241 tgtctgtagt tcttgtcatt tgtagcctga ggccgtggag tccagatttt gggttcagaa
    15301 gttactggaa ttcactatcc catcccattg gtcagaccat gtcactcatt tcaaatacag
    15361 tttggttcat tttttctgat ttcattccat tctaggattc tcctcccatc cttgttggtt
    15421 tatcttcttt tttgagacga agtctcgctc tgtcgcccag gctggagtgc agtggtgcga
    15481 cgtcagctca cggcattctc cgcctcccag gttcaagcaa ttctcctgcc tcagcctcct
    15541 gcgtagctgg gattacaggc gcctgccacc atgcccagct agtttttgta tttttattag
    15601 agacagggtt ttactatgtt agacagcctg gtctcgaact cctgccatca tgatccgcct
    15661 gcctcggcct cccaaagtgc tgggattaca agcatgagcc accacgcccc gcctatgttc
    15721 ctttttttta gaaacgtgaa acctgaactt ggttccaaaa gtcacaacaa aaaggaaaac
    15781 tcctggccgg gcggtggctc acgcctataa tcccagcact tcgggaggcc gaggcgggtg
    15841 gatcacctga ggtcaggagt ttgacaccag cctgaccaac atggtgaaac ccgtctctcc
    15901 taaaaataca aaaacttagc tgggtgtggt ggtgcacgcc tgtaatccca gctgctcggg
    15961 aggctgaggc aggagaattg cttcaaccca ggaagcagag gttgcagtga gctgagatcg
    16021 cgccactgca ctccagcctg cgtgacagac tatctcaaaa aaaaagtaaa actcggccgg
    16081 gcgcggtggc tcacgcctgt aatcccagca ctttgggagg ccgaggcggg cggatcacaa
    16141 ggtcaggaga tcaagacaat cctggccaac atgatgaaac cccatcttta ttaaaagtac
    16201 aaaaaaaaat tagccgggcg tagtggcgta cgcccgtaat cccagctact cgggaggctg
    16261 aggcaggaga atcgcttgaa cccgggaggc agaggttgca gtgagccagg attgtgccac
    16321 tgcactccag cctggtgaca gagcaggact ccatctcaaa aaaaaaaaaa aaaaagtaaa
    16381 actcaagagt agggtgtccc ttcctctcct ccctgttgcc ctggctgaac catctcccct
    16441 gtcttgtttg tcacagatcc cagcatggtg agtgcctaca tgtacccagc aggggccact
    16501 ggggcgcagg cggcccccca ggcccaggcc ggacccaccg ccagccccgc ttactcatcc
    16561 taccagccta ctcccacagc gggctaccag gtacacagga aggccgctcc tctccttcca
    16621 gggccagccc cagccccagc cccagcccca gccccttctc ccatggcact cattccctcc
    16681 gcagaacgtg gcctcccagg ccccacagag cctcccggcc atctctcagc ctccgcagtc
    16741 cagcaccatg ggctacatgg ggagccagtc agtctccatg ggctaccagc cttacaacat
    16801 gcaggtacag tgacctccag gccctgctgg gggccagggt gggggagcag ttgatgatgc
    16861 tgagggtcct ttggtgaggc tggcaggcac tgggtgggct ccaccccttc tgctcctccc
    16921 cctccactct ctgggtgctc cctgtggtca cctttggatt gttgcaagcc agaaacatcc
    16981 ccgcctgcct ggtcacaggg ctactctctc acatctgacg tcttctcaca acagaatctc
    17041 atgaccaccc tcccaagcca ggatgcgtct ctgccacccc agcagcccta catcgcgggg
    17101 cagcagccca tgtaccagca ggtgagccat tcccggggcc tcacagcggc acccgcaggg
    17161 caccctcagg cttcacggtt tagcaatggg acccctggcc ccagtgggga ttgtcccgta
    17221 cgtctgctca cagggggaga cgcatacccg aggccccttc tcagcagaca gaacgaggac
    17281 acaagtctca gggcagatac gcgcatccgc aagtgtagac aggaaaaacc gtgaatttac
    17341 ttgaaaggca aaggccgcat gagctggctg catgagctgc agtccgtgga catggattac
    17401 aagcacttgt gggtctgtgg ctctgctggg acaaaagcct tcctccctgg gctggggaag
    17461 ggaggaccag ggccatgcct gctttcctcc tgcacagatg gcaccctctg gcggtccccc
    17521 ccagcagcag ccccccgtgg cccagcaacc gcaggcacag gggccgccgg cacagggcag
    17581 cgaggcccag ctcatttcat tcgactgacc caggccatgc tcacgtccgg agtaacacta
    17641 catacagttc acctgaaacg cctcgtctct aactgccgtc gtcctgcctc cctgtcctct
    17701 actgccggta gtgtcccttc tctgcgagtg agggggggcc ttcaccccaa gcccacctcc
    17761 cttgtcctca gcctactgca gtccctgagt tagtctctgc tttctttccc cagggctggg
    17821 ccatggggag ggaaggactt tctcccaggg gaagccccca gccctgtggg tcatggtctg
    17881 tgagaggtgg caggaatggg gaccctcacc ccccaagcag cctgtgccct ctggccgcac
    17941 tgtgagctgg ctgtggtgtc tgggtgtggc ctggggctcc ctctgcaggg gcctctctcg
    18001 gcagccacag ccaagggtgg aggcttcagg tctccagctt ctctgcttct cagctgccat
    18061 ctccagtgcc ccagaatggt acagcgataa taaaatgtat ttcagaaagc a
//

